REACH Annex XVII, entry 56: Methylenediphenyl diisocyanate (MDI) including the following specific isomers: (a) ...
Entry 56 covers: Methylenediphenyl diisocyanate (MDI) including the following specific isomers: (a) 4,4’-Methylenediphenyl diisocyanate: (b) ... The first condition begins: "1. Shall not be placed on the market after 27 December 2010, as a constituent of mixtures in ..."
- Annex
- XVII: Restrictions on the manufacture, placing on the market and use of certain dangerous substances, mixtures and articles
- Entry number
- 56
- CAS numbers in the designation
- 26447-40-5, 101-68-8, 5873-54-1, 2536-05-2
- Version
- Consolidated version of 22 June 2026
- Official source
- Regulation (EC) No 1907/2006 (REACH), consolidated text
Designation of the substance, of the group of substances or of the mixture (official wording)
Methylenediphenyl diisocyanate (MDI)
CAS No 26447-40-5
EC No 247-714-0
including the following specific isomers:
(a) 4,4’-Methylenediphenyl diisocyanate:
CAS No 101-68-8
EC No 202-966-0;
(b) 2,4’-Methylenediphenyl diisocyanate:
CAS No 5873-54-1
EC No 227-534-9;
(c) 2,2’-Methylenediphenyl diisocyanate:
CAS No 2536-05-2
EC No 219-799-4
Conditions of restriction (official wording)
1. Shall not be placed on the market after 27 December 2010, as a constituent of mixtures in concentrations equal to or greater than 0,1 % by weight of MDI for supply to the general public, unless suppliers shall ensure before the placing on the market that the packaging:
(a) contains protective gloves which comply with the requirements of Council Directive 89/686/EEC (*9);
(b) is marked visibly, legibly and indelibly as follows, and without prejudice to other Community legislation concerning the classification, packaging and labelling of substances and mixtures:
‘- Persons already sensitised to diisocyanates may develop allergic reactions when using this product.
- Persons suffering from asthma, eczema or skin problems should avoid contact, including dermal contact, with this product.
- This product should not be used under conditions of poor ventilation unless a protective mask with an appropriate gas filter (i.e. type A1 according to standard EN 14387) is used.’
2. By way of derogation, paragraph 1(a) shall not apply to hot melt adhesives.
Introductory text of Annex XVII
For substances which have been incorporated in this Annex as a consequence of restrictions adopted in the framework of Directive 76/769/EEC (Entries 1 to 58), the restrictions shall not apply to storage, keeping, treatment, filling into containers, or transfer from one container to another of these substances for export, unless the manufacture of the substances is prohibited.
Neighbouring entries
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